"ONE TEABAG IS BETTER THAN FOUR": PARTICIPANTS RESPONSE TO THE DISCONTINUATION OF 2% PRO2000/5 MICROBICIDE GEL IN KWAZULU-NATAL, SOUTH AFRICA.

"One teabag is better than four": Participants response to the discontinuation of 2% PRO2000/5 microbicide gel in KwaZulu-Natal, South Africa.

The Microbicides Development Programme evaluated the safety and effectiveness of 0.5% and 2% PRO2000/5 microbicide gels in reducing the risk of vaginally acquired HIV.In February 2008 the Independent Data Monitoring Committee recommended that evaluation of 2% PRO2000/5 gel be discontinued due to futility.The Africa Centre site systematically collec

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In silico-based vaccine design against Ebola virus glycoprotein

Raju Dash,1 Rasel Das,2 Md Junaid,3 Md Forhad Chowdhury Akash,4 Ashekul Islam,5 SM Zahid Hosen1 1Molecular Modeling and Drug Design Laboratory (MMDDL), Pharmacology Research Division, Bangladesh Council of Scientific and Industrial Research (BCSIR), Chittagong, Bangladesh; 2Nanotechnology and Catalysis Research Center, University of Malaya, Kuala L

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Statistical tests for natural selection on regulatory regions based on the strength of transcription factor binding sites

Abstract Background Although cis-regulatory changes play an important role in evolution, it remains difficult to establish the contribution of natural selection to regulatory differences between species.For protein coding regions, powerful tests of natural selection have been developed based on comparisons of synonymous and non-synonymous substitut

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An ecological analysis of walkability and housing affordability in copyright: Moderation by city size and neighbourhood property type composition.

The neighbourhood built environment can support the physical activity of adults regardless of their individual-level socioeconomic status.However, physical activity supportive (walkable) neighbourhoods may not be accessible to those with lower incomes if homes in walkable neighbourhoods are too expensive.The objectives of this study were: 1) to est

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